Blockworks’ Permissionless IV to Unite DeFi’s Top Developers and Builders in Brooklyn

Blockworks’ flagship event, Permissionless IV, is set to return to Industry City in Brooklyn, New York, from June 24-26, bringing together more than 100 of the world’s top technical founders, developers, and thought leaders in DeFi, blockchain infrastructure, and on-chain applications.

Permissionless IV promises to be an unmissable event for builders, developers, innovators, and investors alike, featuring three days of dynamic programming, curated networking, workshops, and cutting-edge activations. The conference will dive deep into the most pressing topics and innovation striking the Web3 space, offering forward-thinking discussions on DeFi, protocol design, tokenomics, and the evolution of on-chain consumer applications.

Attendees will have the opportunity to engage with both the experts and pioneers in blockchain, AI integration, decentralized infrastructure, and more, exploring how these technologies are revolutionizing industries and global markets.

Some of the most respected voices in the onchain world will be in attendance, including:

• Peter Todd, Founder, OpenTimestamps
• Kain Warwick, Founder, Infinex
• Hayden Adam, Founder & CEO, Uniswap
• Guy Young, Founder, Ethena Labs
• Jill Gunter, Co-Founder, Espresso Systems
• Danny Ryan, Co-Founder, Etherealize
• Eli-Ben Sasson, Co-Founder, StarkWare
• Joshua Tobkin, Co-Founder, Supra
• Sreeram Kannan, Founder, EigenLayer

“Permissionless will be the largest gathering of crypto developers in the US this year. It will be the only event that brings together traditional tech developers with crypto-native developers,” said Jason Yanowitz, the Co-Founder of Blockworks. “At a time when every big company in the world is considering their crypto and digital asset strategy, Permissionless is where those decisions will take place.”

Permissionless IV will feature high-impact keynotes, panel discussions, a hackathon, workshops, and networking sessions split across six core themes, including:

• DeFi Renaissance: Exploring real-world assets, US-based capital formation, and the reshoring of DeFi talent.
• Consumer Apps: Delving into onchain applications, mobile apps, prediction markets, NFTs, gaming, and the creator economy.
• Protocol R&D: Discussing blockchain design, EVM, SVM, modular vs. monolithic architectures, rollups, scaling solutions, privacy, and zero-knowledge proofs.
• Token Design: Analyzing tokenomics, token generation events, utility, governance, and equity considerations.
• Crypto x AI: Investigating the intersection of open-source models, onchain verifiability, decentralized physical infrastructure networks (DePIN), agents, decentralized GPUs, and incentivized training.
• Bitcoin: Focusing on Bitcoin dominance, network development, scaling solutions, and institutional and nation-state adoption.

To secure your place at Permissionless IV 2025, purchase tickets here.

Permissionless 2025 is made possible by the following sponsors:

• Ruby Sponsors: Aptos, Blockdaemon, Core, Supra
• Platinum Sponsors: Arkham, Google, Hemi, Infinex, M0, Marinade, Peaq, Rootstock, WOW.AI

About Permissionless

Produced by Blockworks, Permissionless is an annual conference designed as a premier gathering for the crypto and Web3 community. It brings together developers, founders, investors, and enthusiasts to explore the latest trends and innovations in decentralized finance (DeFi), blockchain infrastructure, and onchain applications.

About Blockworks

Blockworks is a crypto media and information platform that delivers breaking news and premium insights about digital assets to millions of investors. Blockworks' editorial content, research, newsletters, and podcasts provide expert analysis to help investors navigate the markets. With flagship events, Permissionless and the Digital Asset Summits (DAS), Blockworks creates space for innovators to build the future of the global economy.

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